{"id":167,"date":"2026-06-05T15:33:04","date_gmt":"2026-06-05T13:33:04","guid":{"rendered":"https:\/\/ideas.stat.unipd.it\/?page_id=167"},"modified":"2026-07-20T11:55:17","modified_gmt":"2026-07-20T09:55:17","slug":"physical-frailty","status":"publish","type":"page","link":"https:\/\/ideas.stat.unipd.it\/index.php\/publications\/physical-frailty\/","title":{"rendered":"Physical frailty"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"167\" class=\"elementor elementor-167\">\n\t\t\t\t<div class=\"elementor-element elementor-element-00879a1 e-flex e-con-boxed e-con e-parent\" data-id=\"00879a1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-347af59 elementor-widget elementor-widget-html\" data-id=\"347af59\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<style>\r\npa {\r\n    font-size: 18px;\r\n        text-align: justify;\r\n}\r\n\r\n@media (min-width: 1025px) {\r\n  .mio-spazio {\r\n    height: 40px;\r\n  }\r\n}\r\n\r\n<\/style>\r\n\r\n<section class=\"Research lines\">\r\n    \r\n    <div class=\"mio-spazio\"><\/div>\r\n    \r\n    \r\n    <h1>Publications on Physical frailty<\/h1>\r\n\r\n\r\n<\/section>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31fab80 elementor-widget elementor-widget-html\" data-id=\"31fab80\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<style>\r\n\r\n.publication-list{\r\n    max-width:950px;\r\n    margin:40px auto;\r\n    font-family:Arial,sans-serif;\r\n}\r\n\r\n.publication{\r\n    border:1px solid #d9d9d9;\r\n    border-radius:10px;\r\n    margin-bottom:25px;\r\n    background:#fff;\r\n    overflow:hidden;\r\n    box-shadow:0 2px 8px rgba(0,0,0,.05);\r\n}\r\n\r\n.publication summary{\r\n    list-style:none;\r\n    cursor:pointer;\r\n    padding:22px 25px 0;\r\n}\r\n\r\n.publication summary::-webkit-details-marker{\r\n    display:none;\r\n}\r\n\r\n.pub-title{\r\n    font-size:22px;\r\n    font-weight:700;\r\n    margin-bottom:10px;\r\n    color:#222;\r\n}\r\n\r\n.pub-authors{\r\n    font-size:17px;\r\n    color:#555;\r\n    margin-bottom:10px;\r\n}\r\n\r\n.pub-journal{\r\n    font-size:15px;\r\n    color:#777;\r\n    margin-bottom:18px;\r\n}\r\n\r\n.pub-toolbar{\r\n    display:flex;\r\n    justify-content:space-between;\r\n    align-items:center;\r\n    flex-wrap:wrap;\r\n    border-top:1px solid #ececec;\r\n    margin-left:-25px;\r\n    margin-right:-25px;\r\n    padding:14px 25px;\r\n}\r\n\r\n.pub-links{\r\n    display:flex;\r\n    gap:18px;\r\n    flex-wrap:wrap;\r\n}\r\n\r\n.pub-links a{\r\n    text-decoration:none;\r\n    color:#444;\r\n    font-size:15px;\r\n}\r\n\r\n.pub-type{\r\n    font-size:13px;\r\n    font-weight:600;\r\n    color:#666;\r\n    text-transform:uppercase;\r\n    letter-spacing:.6px;\r\n    margin-bottom:8px;\r\n}\r\n\r\n.pub-links a:hover{\r\n    color:#0056b3;\r\n}\r\n\r\n.right-tools{\r\n    display:flex;\r\n    align-items:center;\r\n    gap:12px;\r\n}\r\n\r\n.bibtex-btn{\r\n    border:1px solid #d6d6d6;\r\n    background:white;\r\n    padding:8px 14px;\r\n    border-radius:8px;\r\n    cursor:pointer;\r\n    transition:.2s;\r\n}\r\n\r\n.bibtex-btn:hover{\r\n    background:#f3f3f3;\r\n}\r\n\r\n.arrow{\r\n    font-size:20px;\r\n    transition:.3s;\r\n}\r\n\r\n.publication[open] .arrow{\r\n    transform:rotate(180deg);\r\n}\r\n\r\n.abstract{\r\n    border-top:1px solid #ececec;\r\n    padding:25px;\r\n    background:#fafafa;\r\n}\r\n\r\n.abstract h4{\r\n    margin-top:0;\r\n}\r\n\r\n.abstract p{\r\n    line-height:1.7;\r\n    text-align:justify;\r\n}\r\n\r\n@media(max-width:768px){\r\n\r\n.pub-toolbar{\r\n    flex-direction:column;\r\n    align-items:flex-start;\r\n    gap:15px;\r\n}\r\n\r\n.right-tools{\r\n    width:100%;\r\n    justify-content:space-between;\r\n}\r\n\r\n}\r\n\r\n<\/style>\r\n\r\n\r\n\r\n\r\n<div class=\"publication-list\">\r\n\r\n<details class=\"publication\">\r\n\r\n<summary>\r\n\r\n<div class=\"pub-type\">\r\nConference Proceedings\r\n<\/div>\r\n\r\n<div class=\"pub-title\">\r\nEvaluating Frailty Among Older Adults Using a Principal Components-Based Indicator\r\n<\/div>\r\n\r\n<div class=\"pub-authors\">\r\nElettra Bortolotto, Pietro Belloni\r\n<\/div>\r\n\r\n<div class=\"pub-journal\">\r\nStatistical Science: From Theory to Applied Research II \u2013 SIS2026 \u2022 2026 \u2022 pp. 356-362\r\n<\/div>\r\n\r\n<div class=\"pub-toolbar\">\r\n\r\n<div class=\"pub-links\">\r\n\r\n<a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-032-30877-1_58\" target=\"_blank\">\r\n\ud83d\udd17 URL\r\n<\/a>\r\n\r\n<a href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-032-30877-1.pdf\" target=\"_blank\">\r\n\ud83d\udcdd PDF\r\n<\/a>\r\n\r\n<a href=\"https:\/\/scholar.google.com\/scholar?hl=it&as_sdt=0%2C5&q=Evaluating+Frailty+Among+Older+Adults+Using+a+Principal+Components-Based+Indicator&btnG=\" target=\"_blank\">\r\n\ud83c\udf93 Scholar\r\n<\/a>\r\n\r\n<a>\r\n\ud83d\udcc4 DOI: 10.1007\/978-3-032-30877-1_58\r\n<\/a>\r\n\r\n<\/div>\r\n\r\n<div class=\"right-tools\">\r\n\r\n<button class=\"bibtex-btn\" onclick=\"copyBibtex(event,'bib25')\">\r\n    \ud83d\udccb <span>Copy BibTeX<\/span>\r\n<\/button>\r\n\r\n<div class=\"arrow\">\r\n\u25bc\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/summary>\r\n\r\n<div class=\"abstract\">\r\n\r\n<h4>Abstract<\/h4>\r\n\r\n<p>\r\n\r\nPopulation ageing is an expanding phenomenon, driven by increased life expectancy and declining fertility, leading to higher prevalence of chronic-degenerative conditions and growing pressure on care services. Therefore, early identification of frail subjects is essential to protect older adults. This study proposes a new frailty indicator developed using administrative health data from the ULSS6 Euganea(ULSS6 Euganea is a health authority that manages the health care of the population of the 101 municipalities in the province of Padua (located in north-east of Italy), which has approximately 936000 inhabitants.) and including all individuals aged at least 65 years, observed between 2016 and 2017. Six distinct outcomes were chosen to represent frailty, each associated with a specific group of previously identified determinants. For each outcome, a logistic regression was estimated and a principal component analysis was applied to the values predicted by the models, identifying the indicator in the first component. Different frailty stratification methods were compared, including quantiles, the F1-score, and the k-means method. The indicator was validated using two different cohorts, which also made it possible to evaluate its temporal evolution.\r\n\r\n<\/p>\r\n\r\n<\/div>\r\n\r\n<pre id=\"bib25\" style=\"display:none;\">\r\n@inproceedings{bortolotto2026evaluating,\r\n  title={Evaluating Frailty Among Older Adults Using a Principal Components-Based Indicator},\r\n  author={Bortolotto, Elettra and Belloni, Pietro},\r\n  booktitle={Statistical Science: From Theory to Applied Research II: SIS-FENStatS 2026, Short Papers, Contributed Sessions 1},\r\n  pages={356--362},\r\n  year={2026},\r\n  organization={Springer}\r\n}\r\n<\/pre>\r\n\r\n<\/details>\r\n\r\n<\/div>\r\n\r\n\r\n<div class=\"publication-list\">\r\n\r\n<details class=\"publication\">\r\n\r\n<summary>\r\n\r\n<div class=\"pub-type\">\r\nScientific article\r\n<\/div>\r\n\r\n<div class=\"pub-title\">\r\nIdentifying core adverse health outcomes for frailty assessment in older adults using administrative data\r\n<\/div>\r\n\r\n<div class=\"pub-authors\">\r\nMargherita Silan, Maurizio Nicolaio, Erika Banzato, Giovanna Boccuzzo\r\n<\/div>\r\n\r\n<div class=\"pub-journal\">\r\nFrontiers in medicine \u2022 2025 \u2022 Vol. 12\r\n<\/div>\r\n\r\n<div class=\"pub-toolbar\">\r\n\r\n<div class=\"pub-links\">\r\n\r\n<a href=\"https:\/\/www.frontiersin.org\/journals\/medicine\/articles\/10.3389\/fmed.2025.1678317\/full\" target=\"_blank\">\r\n\ud83d\udd17 URL\r\n<\/a>\r\n\r\n<a href=\"https:\/\/www.frontiersin.org\/journals\/medicine\/articles\/10.3389\/fmed.2025.1678317\/pdf\" target=\"_blank\">\r\n\ud83d\udcdd PDF\r\n<\/a>\r\n\r\n<a href=\"https:\/\/scholar.google.com\/scholar?hl=it&as_sdt=0%2C5&q=Identifying+core+adverse+health+outcomes+for+frailty+assessment+in+older+adults+using+administrative+data&btnG=\" target=\"_blank\">\r\n\ud83c\udf93 Scholar\r\n<\/a>\r\n\r\n<a  >\r\n\ud83d\udcc4 DOI: 10.3389\/fmed.2025.1678317\r\n<\/a>\r\n\r\n\r\n\r\n<\/div>\r\n\r\n<div class=\"right-tools\">\r\n\r\n<button class=\"bibtex-btn\" onclick=\"copyBibtex(event,'bib12')\">\r\n    \ud83d\udccb <span>Copy BibTeX<\/span>\r\n<\/button>\r\n\r\n<div class=\"arrow\">\r\n\u25bc\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/summary>\r\n\r\n<div class=\"abstract\">\r\n\r\n<h4>Abstract<\/h4>\r\n\r\n<p>\r\n\r\nObjectives: Measurement of frailty can be based on the ability to predict adverse health outcomes. Although frailty research is progressing rapidly, a unique work that analyzes together outcomes related to frailty condition is still lacking in literature. This article aims to fill this gap, selecting a parsimonious set of outcomes relevant in frailty studies that exploit administrative healthcare data. <br>\r\nMethods: Starting with an extensive literature review, we identified several health outcomes that can be measured with administrative healthcare databases. We computed the prevalence and correlation of these outcomes in a local health unit in North-East Italy. We performed a factor analysis and estimated a graphical model to examine the conditional independence relationships between the outcomes. <br>\r\nResults: Our analysis revealed two primary outcome groups: adverse events (characterized by various forms of hospital use) and adverse conditions (such as dementia and disability). Femur fracture emerged as a distinct outcome, while death showed positive associations with all other outcomes. Considering overlaps and relationships, we selected a core set of six representative outcomes: death, high priority access to the emergency room, femur fracture, hospitalization, disability, and dementia. <br>\r\nConclusion: This study identified six central and non-redundant adverse health outcomes related to frailty that can be easily derived from routinely available administrative healthcare data. These findings provide a methodologically grounded selection of outcomes that are clinically meaningful and feasible, offering a solid foundation for developing population-based frailty indices.\r\n\r\n<\/p>\r\n\r\n<\/div>\r\n\r\n<pre id=\"bib12\" style=\"display:none;\">\r\n@article{silan2025identifying,\r\n  title={Identifying core adverse health outcomes for frailty assessment in older adults using administrative data},\r\n  author={Silan, Margherita and Nicolaio, Maurizio and Banzato, Erika and Boccuzzo, Giovanna},\r\n  journal={Frontiers in Medicine},\r\n  volume={12},\r\n  pages={1678317},\r\n  year={2025},\r\n  publisher={Frontiers Media SA}\r\n}\r\n<\/pre>\r\n\r\n<\/details>\r\n\r\n<\/div>\r\n\r\n\r\n<div class=\"publication-list\">\r\n\r\n<details class=\"publication\">\r\n\r\n<summary>\r\n\r\n<div class=\"pub-type\">\r\nBook chapter\r\n<\/div>\r\n\r\n<div class=\"pub-title\">\r\nBeyond longevity. Measuring frailty to inform health policy and practice \r\n<\/div>\r\n\r\n<div class=\"pub-authors\">\r\nGiovanna Boccuzzo, Margherita Silan, Maurizio Nicolaio, Annalisa Donno, Enrico Bovo\r\n<\/div>\r\n\r\n<div class=\"pub-journal\">\r\nAssociazione Neodemos \u2022 2025 \u2022 pp. 79-86\r\n<\/div>\r\n\r\n<div class=\"pub-toolbar\">\r\n\r\n<div class=\"pub-links\">\r\n\r\n<a href=\"https:\/\/www.niussp.org\/ebooks\/age-it-and-the-promiseof-positive-demography-rethinking-ageing-with-sustainable-policies\/\" target=\"_blank\">\r\n\ud83d\udd17 URL\r\n<\/a>\r\n\r\n<a href=\"https:\/\/www.niussp.org\/wp-content\/uploads\/2025\/11\/English_Version_ageit_def.pdf\" target=\"_blank\">\r\n\ud83d\udcdd PDF\r\n<\/a>\r\n\r\n<a href=\"https:\/\/scholar.google.com\/scholar?hl=it&as_sdt=0%2C5&q=Beyond+longevity.+Measuring+frailty+to+inform+health+policy++and+practice&btnG=\" target=\"_blank\">\r\n\ud83c\udf93 Scholar\r\n<\/a>\r\n\r\n<a  >\r\n\ud83d\udcd6 ISBN: 978-88-32003-17-8\r\n<\/a>\r\n\r\n\r\n\r\n<\/div>\r\n\r\n<div class=\"right-tools\">\r\n\r\n<button class=\"bibtex-btn\" onclick=\"copyBibtex(event,'bib10')\">\r\n    \ud83d\udccb <span>Copy BibTeX<\/span>\r\n<\/button>\r\n\r\n<div class=\"arrow\">\r\n\u25bc\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/summary>\r\n\r\n<div class=\"abstract\">\r\n\r\n<h4>Introduction<\/h4>\r\n\r\n<p>\r\n\r\nThe increase in life expectancy is one of the greatest achievements of modern societies. However, the so-called \u2018longevity paradox\u2019, described by Fries in 1980 and, more recently, by Garmany and colleagues, shows that the additional years are not always lived in good health. In Italy, life expectancy at birth rose from 79.6 years in 2000 to 83.4 years in 2019. Naghavi and the Global Burden of Disease group have calculated that healthy life expectancy (HALE) increased from 68.5 years (95% CI: 65.271.3) in 2000 to 70.9 years (67.4\u201373.8) in 2021, confirming that longer lives do not necessarily translate into years lived in full independence. The issue is not purely medical: it concerns health systems, families, and the sustainability of social services. Over the last two decades, the concept of \u2018frailty\u2019 has become central to explaining why some older people, even without serious disease, are more vulnerable to adverse events such as falls, hospital admissions, loss of autonomy, and mortality. Recognising and measuring frailty is crucial for public health and for the planning of preventive interventions.\r\n\r\n<\/p>\r\n\r\n<\/div>\r\n\r\n<pre id=\"bib10\" style=\"display:none;\">\r\n@incollection{boccuzzo2025,\r\n  author    = {Boccuzzo, Giovanna and Silan, Margherita and Nicolaio, Maurizio and Donno, Annalisa and Bovo, Enrico and others},\r\n  title     = {Beyond Longevity: Measuring Frailty to Inform Health Policy and Practice},\r\n  booktitle = {Age-It and the Promise of Positive Demography},\r\n  editor    = {Vignoli, Daniele and De Santis, Gustavo},\r\n  publisher = {Neodemos},\r\n  year      = {2025},\r\n  pages      = {79--86}\r\n}\r\n<\/pre>\r\n\r\n<\/details>\r\n\r\n<\/div>\r\n\r\n\r\n<div class=\"publication-list\">\r\n\r\n<details class=\"publication\">\r\n\r\n<summary>\r\n\r\n<div class=\"pub-type\"> Book chapter <\/div>\r\n\r\n<div class=\"pub-title\">\r\nLa Fragilit\u00e0 negli anziani: comprenderla e misurarla per orientare le politiche sanitarie\r\n<\/div>\r\n\r\n<div class=\"pub-authors\">\r\nGiovanna Boccuzzo, Margherita Silan, Maurizio Nicolaio, Annalisa Donno, Enrico Bovo\r\n<\/div>\r\n\r\n<div class=\"pub-journal\">\r\nAssociazione Neodemos \u2022 2025 \u2022 pp. 84-92 \r\n<\/div>\r\n\r\n<div class=\"pub-toolbar\">\r\n\r\n<div class=\"pub-links\">\r\n\r\n<a href=\"https:\/\/www.neodemos.info\/2025\/10\/29\/age-it-e-la-promessa-di-una-demografia-positiva-ripensare-linvecchiamento-con-politiche-sostenibili\/\" target=\"_blank\">\r\n\ud83d\udd17 URL\r\n<\/a>\r\n\r\n<a href=\"https:\/\/www.neodemos.info\/wp-content\/uploads\/2025\/10\/E-book_ageit_definitivo-1.pdf\" target=\"_blank\">\r\n\ud83d\udcdd PDF\r\n<\/a>\r\n\r\n<a href=\"https:\/\/scholar.google.com\/scholar?hl=it&as_sdt=0%2C5&q=LA+FRAGILIT%C3%80+NEGLI+ANZIANI%3A+COMPRENDERLA+E+MISURARLA+PER+ORIENTARE+LE+POLITICHE+SANITARIE&btnG=\" target=\"_blank\">\r\n\ud83c\udf93 Scholar\r\n<\/a>\r\n\r\n<a  >\r\n\ud83d\udcd6 ISBN: 978-88-32003-15-4\r\n<\/a>\r\n\r\n\r\n\r\n<\/div>\r\n\r\n<div class=\"right-tools\">\r\n\r\n<button class=\"bibtex-btn\" onclick=\"copyBibtex(event,'bib7')\">\r\n    \ud83d\udccb <span>Copy BibTeX<\/span>\r\n<\/button>\r\n\r\n<div class=\"arrow\">\r\n\u25bc\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/summary>\r\n\r\n<div class=\"abstract\">\r\n\r\n<h4>Introduction<\/h4>\r\n\r\n<p>\r\n\r\nL\u2019aumento della longevit\u00e0 \u00e8 uno dei pi\u00f9 grandi successi delle societ\u00e0 moderne. Tuttavia, il cosiddetto \u201cparadosso della longevit\u00e0\u201d, ben descritto, fra gli altri, da Fries  nel 1980 e da Garmany e colleghi in anni pi\u00f9 recenti, mostra che gli anni guadagnati non sempre sono vissuti in buona salute. In Italia, la speranza di vita alla nascita \u00e8 aumentata da 79,6 anni nel 2000 a 83,4 anni nel 2019. Naghavi e il gruppo Global Burden of Disease hanno calcolato che la speranza di vita in buona salute (HALE) \u00e8 aumentata da 68,5 anni (IC 95%: 65,2\u201371,3) nel 2000 a 70,9 anni (67,4\u201373,8) nel 2021, confermando che l\u2019allungamento della vita non si traduce in pari misura in anni vissuti in piena autonomia. Il problema non \u00e8 solo medico: riguarda i sistemi sanitari, le famiglie, la sostenibilit\u00e0 dei servizi sociali. Negli ultimi vent\u2019anni il concetto di \u201cfragilit\u00e0\u201d (frailty) \u00e8 diventato fondamentale per spiegare perch\u00e9 alcune persone anziane, anche senza malattie gravi, siano pi\u00f9 vulnerabili a eventi avversi come cadute, ricoveri, perdita di autonomia e morte. Riconoscere e misurare la fragilit\u00e0 \u00e8 cruciale per la sanit\u00e0 pubblica e per la programmazione di interventi di prevenzione.\r\n\r\n<\/p>\r\n\r\n<\/div>\r\n\r\n<pre id=\"bib7\" style=\"display:none;\">\r\n@incollection{boccuzzo2025fragilita,\r\n  title={LA FRAGILIT{\\`A} NEGLI ANZIANI: COMPRENDERLA E MISURARLA PER ORIENTARE LE POLITICHE SANITARIE},\r\n  author={Boccuzzo, G and Silan, M and Donno, A and Nicolaio, M and Bovo, E and others},\r\n  booktitle={AGE-IT E LA PROMESSA DI UNA DEMOGRAFIA POSITIVA. Ripensare l\u2019invecchiamento con politiche sostenibili},\r\n  pages={84--92},\r\n  year={2025},\r\n  publisher={NeoDemos}\r\n}\r\n<\/pre>\r\n\r\n<\/details>\r\n\r\n<\/div>\r\n\r\n\r\n<div class=\"publication-list\">\r\n\r\n<details class=\"publication\">\r\n\r\n<summary>\r\n\r\n<div class=\"pub-type\">\r\nBook\r\n<\/div>\r\n\r\n<div class=\"pub-title\">\r\nMisurare la fragilit\u00e0 negli anziani. Metodi e strumenti a supporto delle politiche e della ricerca\r\n<\/div>\r\n\r\n<div class=\"pub-authors\">\r\nGiovanna Boccuzzo, Annalisa Donno\r\n<\/div>\r\n\r\n<div class=\"pub-journal\">\r\nFranco Angeli \u2022 2025\r\n<\/div>\r\n\r\n<div class=\"pub-toolbar\">\r\n\r\n<div class=\"pub-links\">\r\n\r\n<a href=\"https:\/\/series.francoangeli.it\/index.php\/oa\/catalog\/book\/1345\" target=\"_blank\">\r\n\ud83d\udd17 URL\r\n<\/a>\r\n\r\n<a href=\"https:\/\/series.francoangeli.it\/index.php\/oa\/catalog\/view\/1345\/1482\/7451\">\r\n\ud83d\udcdd PDF\r\n<\/a>\r\n\r\n<a href=\"https:\/\/scholar.google.com\/scholar?hl=it&as_sdt=0,5&q=Misurare+La+Fragilit%C3%A0+Negli+Anziani\" target=\"_blank\">\r\n\ud83c\udf93 Scholar\r\n<\/a>\r\n\r\n<a  >\r\n\ud83d\udcd6 ISBN: 978-88-35179-50-4\r\n<\/a>\r\n\r\n<\/div>\r\n\r\n<div class=\"right-tools\">\r\n\r\n<button class=\"bibtex-btn\" onclick=\"copyBibtex(event,'bib3')\">\r\n    \ud83d\udccb <span>Copy BibTeX<\/span>\r\n<\/button>\r\n\r\n<div class=\"arrow\">\r\n\u25bc\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/summary>\r\n\r\n<div class=\"abstract\">\r\n\r\n<div class=\"volume-section\">\r\n\r\n  <h4>In this volume:<\/h4>\r\n\r\n  <ul>\r\n    <li>G. Boccuzzo, A. Donno. Prefazione, pp. 9\u201314<\/li>\r\n\r\n    <li>A. Donno, M. Nicolaio, M. Silan, G. Boccuzzo. Cos\u2019\u00e8 la fragilit\u00e0 dell\u2019anziano e come pu\u00f2 essere identificata. pp. 15\u201334<\/li>\r\n\r\n    <li>E. Bovo, G. Boccuzzo. Misure di fragilit\u00e0 sulla base di indagini di popolazione. pp. 35\u201386<\/li>\r\n\r\n    <li>M. Nicolaio, A. Donno, G. Boccuzzo. Indicatori di fragilit\u00e0 sulla base di dati amministrativi. pp. 87\u2013170<\/li>\r\n\r\n    <li>A. Ghirardo, G. Boccuzzo. La fragilit\u00e0 sociale. pp. 194\u2013231<\/li>\r\n\r\n    <li>E. Bovo, A. Donno. La fragilit\u00e0 in Italia. pp. 232\u2013268<\/li>\r\n  <\/ul>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<pre id=\"bib3\" style=\"display:none;\">\r\n@article{boccuzzo2025misurare,\r\n  title={Misurare la fragilit{\\`a} negli anziani: Definizioni e strumenti a supporto delle politiche e della ricerca},\r\n  author={Boccuzzo, Giovanna and Donno, Annalisa},\r\n  year={2025},\r\n  publisher={Franco Angeli}\r\n}\r\n<\/pre>\r\n\r\n<\/details>\r\n\r\n<\/div>\r\n\r\n\r\n<div class=\"publication-list\">\r\n\r\n<details class=\"publication\">\r\n\r\n<summary>\r\n    \r\n    <div class=\"pub-type\"> Scientific article <\/div>\r\n\r\n<div class=\"pub-title\">\r\nAssessing Frailty in Older Adults: Strategies and Tools for Effective Policy and Research\r\n<\/div>\r\n\r\n<div class=\"pub-authors\">\r\nAnnalisa Donno, Margherita Silan, Giovanna Boccuzzo \r\n<\/div>\r\n\r\n<div class=\"pub-journal\">\r\nRivista Italiana di Economia Demografia e Statistica \u2022 2024 \u2022 Vol. 78(3)\r\n<\/div>\r\n\r\n<div class=\"pub-toolbar\">\r\n\r\n<div class=\"pub-links\">\r\n\r\n<a href=\"https:\/\/doi.org\/10.71014\/sieds.v78i3.398\" target=\"_blank\">\r\n\ud83d\udd17 URL\r\n<\/a>\r\n\r\n<a href=\"https:\/\/www.rieds-journal.org\/rieds\/article\/view\/398\/273\" target=\"_blank\">\r\n\ud83d\udcdd PDF\r\n<\/a>\r\n\r\n<a href=\"https:\/\/scholar.google.com\/scholar?hl=it&as_sdt=0%2C5&q=Assessing+Frailty+in+Older+Adults%3A+Strategies+and+Tools+for+Effective+Policy+and+Research&btnG=\" target=\"_blank\">\r\n\ud83c\udf93 Scholar\r\n<\/a>\r\n\r\n<a>\r\n\ud83d\udcc4 DOI: 10.71014\/sieds.v78i3.398\r\n<\/a>\r\n\r\n<\/div>\r\n\r\n<div class=\"right-tools\">\r\n\r\n<button class=\"bibtex-btn\" onclick=\"copyBibtex(event,'bib1')\">\r\n    \ud83d\udccb <span>Copy BibTeX<\/span>\r\n<\/button>\r\n\r\n<div class=\"arrow\">\r\n\u25bc\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/summary>\r\n\r\n<div class=\"abstract\">\r\n\r\n<h4>Abstract<\/h4>\r\n\r\n<p>\r\n\r\nThe progressive ageing of the population, not accompanied by a corresponding increase in healthy life expectancy, brings to the forefront the study of the health of older adults from a holistic perspective. The concept of frailty aligns with this perspective, as it considers a broader condition of vulnerability involving mainly older individuals, which is much more difficult to define and measure. This article aims to provide an overview of the concept of frailty, the various definitional approaches, and, consequently, the measurement methods, while also focussing on the relationship between frailty and the two main concepts that define health: multimorbidity and disability. Following a brief overview of the types of data and their role in the study of frailty, the article concludes with an analytical approach for defining a measure of frailty.\r\n\r\n<\/p>\r\n\r\n<\/div>\r\n\r\n<pre id=\"bib1\" style=\"display:none;\">\r\n@article{donno2024,\r\nauthor={Donno, A. and Silan, M. and Boccuzzo, G.},\r\ntitle={Assessing Frailty in Older Adults: Strategies and Tools for Effective Policy and Research},\r\njournal={Rivista Italiana di Economia Demografia e Statistica},\r\nyear={2024},\r\nvolume={78},\r\nnumber={3},\r\npages={11--38},\r\ndoi={10.71014\/sieds.v78i3.398}\r\n<\/pre>\r\n\r\n<\/details>\r\n\r\n<\/div>\r\n\r\n\r\n<div class=\"publication-list\">\r\n\r\n<details class=\"publication\">\r\n\r\n<summary>\r\n    \r\n    <div class=\"pub-type\"> Scientific article <\/div>\r\n\r\n<div class=\"pub-title\">\r\nConstruction of a Frailty Indicator with Partially Ordered Sets: A Multiple-Outcome Proposal Based on Administrative Healthcare Data\r\n<\/div>\r\n\r\n<div class=\"pub-authors\">\r\nMargherita Silan, Giada Signori, Elisa Ferracin, Elisabetta Listorti, Teresa Spadea, Giuseppe Costa, Giovanna Boccuzzo \r\n<\/div>\r\n\r\n<div class=\"pub-journal\">\r\nSocial Indicators Research \u2022 2022 \u2022 Vol.160, pp. 989\u20131017\r\n<\/div>\r\n\r\n<div class=\"pub-toolbar\">\r\n\r\n<div class=\"pub-links\">\r\n\r\n<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s11205-020-02512-7#citeas\" target=\"_blank\">\r\n\ud83d\udd17 URL\r\n<\/a>\r\n\r\n<a href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11205-020-02512-7.pdf\" target=\"_blank\">\r\n\ud83d\udcdd PDF\r\n<\/a>\r\n\r\n<a href=\"https:\/\/scholar.google.com\/scholar?hl=it&as_sdt=0%2C5&q=Construction+of+a+Frailty+Indicator+with+Partially+Ordered+Sets%3A+A+Multiple-Outcome+Proposal+Based+on+Administrative+Healthcare+Data&btnG=\" target=\"_blank\">\r\n\ud83c\udf93 Scholar\r\n<\/a>\r\n\r\n<a>\r\n\ud83d\udcc4 DOI: 10.1007\/s11205-020-02512-7\r\n<\/a>\r\n\r\n<\/div>\r\n\r\n<div class=\"right-tools\">\r\n\r\n<button class=\"bibtex-btn\" onclick=\"copyBibtex(event,'bib16')\">\r\n    \ud83d\udccb <span>Copy BibTeX<\/span>\r\n<\/button>\r\n\r\n<div class=\"arrow\">\r\n\u25bc\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/summary>\r\n\r\n<div class=\"abstract\">\r\n\r\n<h4>Abstract<\/h4>\r\n\r\n<p>\r\n\r\nGiven the progressive aging of Italian and European populations, the number of cases with chronic diseases is steeply increasing. This calls for new strategies for health resource management and the implementation of prevention policies. Among chronic patients, frail subjects have special and wider care requirements, along with an increased risk of adverse health outcomes. Thus, their identification is an important step for the Italian National Program for Chronic Diseases. This study aims at constructing an indicator that measures the frailty level of individuals in the population aged over 65 y using administrative healthcare data-flows of the Piedmont region. Following the multidimensional nature of frailty, we adopted a multiple-outcome approach in our proposal. This was done by considering the capacity to predict six unfavorable outcomes: death, urgent unplanned hospitalization, access to the emergency room with red code, avoidable hospitalization, hip fracture, and disability. We identified a parsimonious set of seven explanatory variables that can simultaneously predict the six outcomes we considered. We then assembled them into a unique frailty indicator through the use of a partially ordered set (poset) theory. Our indicator performed well with respect to all the outcomes and was able to describe several individual characteristics that are not directly considered in the computation of the indicator. Thanks to its parsimony and to the use of administrative healthcare data, our indicator allows all the stakeholders involved in the healthcare process, such as Italian Local Health Units, general practitioners, and regional managers, to use it to target frail individuals with better comprehensive healthcare actions.\r\n\r\n<\/p>\r\n\r\n<\/div>\r\n\r\n<pre id=\"bib16\" style=\"display:none;\">\r\n@article{silan2022construction,\r\n  title={Construction of a frailty indicator with partially ordered sets: a multiple-outcome proposal based on administrative healthcare data},\r\n  author={Silan, Margherita and Signorin, Giada and Ferracin, Elisa and Listorti, Elisabetta and Spadea, Teresa and Costa, Giuseppe and Boccuzzo, Giovanna},\r\n  journal={Social Indicators Research},\r\n  volume={160},\r\n  number={2},\r\n  pages={989--1017},\r\n  year={2022},\r\n  publisher={Springer}\r\n}\r\n<\/pre>\r\n\r\n<\/details>\r\n\r\n<\/div>\r\n\r\n\r\n<div class=\"publication-list\">\r\n\r\n<details class=\"publication\">\r\n\r\n<summary>\r\n    \r\n    <div class=\"pub-type\"> Scientific article <\/div>\r\n\r\n<div class=\"pub-title\">\r\nQuantifying Frailty in Older People at an Italian Local Health Unit\r\n<\/div>\r\n\r\n<div class=\"pub-authors\">\r\nMargherita Silan, Giulio Caperna, Giovanna Boccuzzo\r\n<\/div>\r\n\r\n<div class=\"pub-journal\">\r\nSocial Indicators Research \u2022 2019 \u2022 Vol.146(3), pp. 757-782\r\n<\/div>\r\n\r\n<div class=\"pub-toolbar\">\r\n\r\n<div class=\"pub-links\">\r\n\r\n<a href=\"https:\/\/www.jstor.org\/stable\/48704919\" target=\"_blank\">\r\n\ud83d\udd17 URL\r\n<\/a>\r\n\r\n<a href=\"https:\/\/www.jstor.org\/stable\/pdf\/48704919.pdf?refreqid=fastly-default%3A857cfd3a89dcd1c16ce0fce2d1984efa&ab_segments=&initiator=&acceptTC=1\" target=\"_blank\">\r\n\ud83d\udcdd PDF\r\n<\/a>\r\n\r\n<a href=\"https:\/\/scholar.google.com\/scholar?hl=it&as_sdt=0%2C5&q=Quantifying+Frailty+in+Older+People+at+an+Italian+Local+Health+Unit&btnG=\" target=\"_blank\">\r\n\ud83c\udf93 Scholar\r\n<\/a>\r\n\r\n<a>\r\n\ud83d\udcc4 DOI: 10.1007\/s11205-019-02142-8\r\n<\/a>\r\n\r\n<\/div>\r\n\r\n<div class=\"right-tools\">\r\n\r\n<button class=\"bibtex-btn\" onclick=\"copyBibtex(event,'bib17')\">\r\n    \ud83d\udccb <span>Copy BibTeX<\/span>\r\n<\/button>\r\n\r\n<div class=\"arrow\">\r\n\u25bc\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n\r\n<\/summary>\r\n\r\n<div class=\"abstract\">\r\n\r\n<h4>Abstract<\/h4>\r\n\r\n<p>\r\n\r\nPopulation aging, which is common in developed countries, highlights issues related to\r\nthe health and social assistance of frail individuals. The Italian Chronic Disease Program\r\nlaunched by the Ministry of Health proposes the implementation of tools that stratify the\r\npopulation based on health and care needs and enhances the integration of existing admin-\r\nistrative health data flows. This work has its roots in the need to identify frail individuals\r\nconveyed by an Italian Local Health Unit (LHU) of the Veneto region and organize an\r\nefficient service of care and prevention. We propose an indicator of frailty, computed using\r\nthe poset approach, comprising only eight variables available in administrative health data\r\nat the LHU level. The proposed indicator associates a value of frailty between 0 and 1 to\r\nevery individual of the population aged 65 years and older, thereby allowing stratification\r\nof the population by the risk level. By validating and analyzing the frailty indicator, we\r\nshow that this approach provides an effective stratification of older people.\r\n\r\n<\/p>\r\n\r\n<\/div>\r\n\r\n<pre id=\"bib17\" style=\"display:none;\">\r\n@article{silan2019quantifying,\r\n  title={Quantifying Frailty in Older People at an Italian Local Health Unit},\r\n  author={Silan, Margherita and Caperna, Giulio and Boccuzzo, Giovanna},\r\n  journal={Social Indicators Research},\r\n  volume={146},\r\n  number={3},\r\n  pages={757--782},\r\n  year={2019},\r\n  publisher={JSTOR}\r\n}\r\n<\/pre>\r\n\r\n<\/details>\r\n\r\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Publications on Physical frailty Conference Proceedings Evaluating Frailty Among Older Adults Using a Principal Components-Based Indicator Elettra Bortolotto, Pietro Belloni Statistical Science: From Theory to<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":53,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-167","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/pages\/167","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/comments?post=167"}],"version-history":[{"count":9,"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/pages\/167\/revisions"}],"predecessor-version":[{"id":1406,"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/pages\/167\/revisions\/1406"}],"up":[{"embeddable":true,"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/pages\/53"}],"wp:attachment":[{"href":"https:\/\/ideas.stat.unipd.it\/index.php\/wp-json\/wp\/v2\/media?parent=167"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}